Senior Security Engineer

Who we are

We’re a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world’s most persistent diseases is not paved by those who play it safe. It is built by those who take pioneering, creative approaches and implement them with quality and excellence.

We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs – in the best possible way.

Our mission is to work with passion and purpose every day to improve lives and we are looking for others who value this same pursuit.

Why Worldwide

We believe everyone plays an important role in making a world of difference for patients and their caregivers. From our hands-on, accessible leaders, to our cohesive and supportive teams, we are committed to enabling professionals from all backgrounds and experiences to succeed. We prioritize cultivating a diverse and inclusive environment that continues to promote collaboration and creativity. We are proud to be a workplace where people thrive by being themselves and are inspired to do their best work every day. Join us!

What the Senior Security Engineer does at Worldwide

The Senior Security Engineer plays a key role in supporting Worldwide Clinical Trials’ Zero Trust and cloud-first security strategy. Reporting to the Senior Director of Information Security, this role is responsible for leading the implementation, management, and optimization of Zscaler technologies across the enterprise. The Senior Engineer works closely with stakeholders across IT, including Infrastructure and Security Operations to ensure consistent enforcement of access control, data protection, and user experience monitoring through Zscaler platform.

What you will do

Tasks may include but are not limited to:

• Design, deploy, and manage Zscaler solutions, including:

  • Zscaler Internet Access (ZIA): URL filtering, SSL inspection, cloud firewall, DNS control, CASB, and DLP.

  • Zscaler Private Access (ZPA): Application segmentation, identity-based access, SAML/SSO integration.

  • Zscaler Digital Experience (ZDX): End-user performance monitoring and diagnostics.

• Lead incident response and troubleshooting related to Zscaler, such as DNS categorization issues, SSL decryption errors, or access anomalies.

• Collaborate with Infrastructure and Security Operations teams to enforce endpoint posture checks, DLP policies, and access control rules across Zscaler platforms.

• Integrate Zscaler logs and telemetry into SIEM platforms to support threat detection, forensics, and compliance reporting.

• Develop and maintain automation scripts and workflows using Zscaler APIs to support policy enforcement, reporting, and operational efficiency.

• Conduct maturity assessments and contribute to the Zscaler roadmap aligned to Zero Trust architecture goals.

• Serve as the subject matter expert (SME) on Zscaler for cross-functional initiatives, vendor engagements, and system design reviews.

• Perform other duties as assigned. The duties and responsibilities listed above are representative of the nature and level of work assigned and are not necessarily all-inclusive.

What you bring to the role

• Deep understanding of Zscaler architecture, deployment models, and policy frameworks.

• Strong analytical and troubleshooting skills, especially in large-scale cloud security environments.

• Proficiency with automation tools and scripting languages (e.g., Python, PowerShell, REST APIs).

• Effective communication skills, capable of translating complex technical topics for both technical and non-technical audiences.

• Familiarity with adjacent technologies such as endpoint detection and response (EDR), identity and access management (IAM), and data loss prevention (DLP).

• Experience working in regulated industries or supporting compliance requirements such as GxP, HIPAA, or GDPR is a plus.

Your experience

• Bachelor’s degree in Computer Science, Information Technology, or related field with a minimum of 5 years of experience in enterprise security engineering, with at least 2 years directly supporting Zscaler solutions or high school diploma/GED with a minimum of 7 years of experience in enterprise security engineering, with at least 2 years directly supporting Zscaler solutions.

• Hands-on experience with ZIA, ZPA, and ZDX in a production environment.

• Strong understanding of cloud security concepts, identity management, and Zero Trust principles.

• Experience with automation for security operations and policy management using APIs.

• Zscaler certifications (ZCCA-IA, ZCCA-PA, ZCCP) are highly desirable.

Promotion to the next level is not automatic based on years of experience. Personnel are evaluated on proven competency, level of responsibility, and ability to work independently.

At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.

The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):

United States of America - $121,500.00 - $240,500.00

The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.

We love knowing that someone is going to have a better life because of the work we do.

To view our other roles, check out our careers page at Discover a world of difference at Worldwide! For more information on Worldwide, visit or connect with us on LinkedIn.