Senior Manager / Manager, LLM Architect

Overview

The Consortium for Clinical Research and Innovation, Singapore (CRIS) brings together six national R&D, clinical translation and service programmes to advance clinical research and innovation for Singapore, and establish important capabilities for a future-ready healthcare system.

The Business Entities under CRIS include:

• Singapore Clinical Research Institute (SCRI)
• National Health Innovation Centre (NHIC)
• Advanced Cell Therapy and Research Institute, Singapore (ACTRIS)
• Precision Health Research, Singapore (PRECISE)
• Singapore Translational Cancer Consortium (STCC)
• Cardiovascular Disease National Collaborative Enterprise (CADENCE)
• Singapore Medical Foundation AI model (SIMFONI)

Together, CRIS makes a positive difference to Singapore patients and researchers by ensuring that these clinical research platforms and programmes are at the cutting edge of capability development and innovation. If you are as passionate as we are in clinical trials and research, we want you!

SIMFONI

The SIngapore Medical FOundation AI model (SIMFONI) Programme was established in 2025 to advance the safe and responsible use of Artificial Intelligence (AI) in Singapore’s public healthcare ecosystem to support healthcare professionals in providing care to patients.

SIMFONI will build up the capabilities and infrastructure to accelerate the development and deployment of large-scale machine learning models, known as Foundation models (FM) for improved healthcare outcomes.

As a Senior Project/Product Manager to lead the research development, integration, and evaluation of AI reasoning models within Singapore’s public healthcare system. The ideal candidate will be a strong systems thinker who can operate across research, clinical, and technical domains to shape innovative AI-enabled tools for real-world impact.

You will oversee multi-party product efforts from concept through proof-of-concept (POC), with a long-term view toward scalable deployment across the national health system. This is a high-impact role at the intersection of public health, technology, and policy—requiring exceptional coordination, clarity of vision, and stakeholder leadership.

The initial focus will be the research and development of a reasoning model for a clinical decision support system supporting the management of cardiometabolic conditions. The candidate will partner closely with multiple project teams to identify and standardise datasets and test vignettes required for FM training and evaluation.

Key Responsibilities

Strategic Product Leadership

• Define and evolve the product vision and roadmap for AI-enabled tools aligned with national healthcare priorities.
• Translate clinical, research, and operational needs into clear, actionable product strategies.
• Identify opportunities to accelerate R&D into impactful, system-ready POCs.

Agile Governance & Delivery

• Lead Agile product processes across diverse and concurrent workstreams.
• Set expectations for sprint delivery, prioritization, and outcome-based planning.
• Coach teams toward disciplined product delivery while adapting to evolving research inputs.

Portfolio & Stakeholder Management

• Coordinate across multiple AI research streams, ensuring aligned milestones, governance, and evaluation frameworks.
• Serve as the senior liaison among clinicians, technical leads, researchers, public sector stakeholders, and regulatory bodies.
• Resolve strategic trade-offs and align cross-sector interests toward shared healthcare outcomes.

Integration & System Readiness

• Guide convergence of prototypes into integrated solutions suitable for clinical proof-of-concept deployment.
• Work with implementation teams to plan for system integration, change management, and user adoption.
• Identify scale-up considerations early, including interoperability, governance, and workforce impact.

Risk, Ethics & Regulatory Readiness

• Embed responsible AI principles, privacy safeguards, and patient safety from the outset.
• Support documentation and coordination for Software as a Medical Device (SaMD) classification and related regulatory needs.
• Ensure that AI tools meet standards of transparency, accountability, and public trust.

Requirements

• At least 6 years of experience in product management or related leadership roles, ideally in healthcare, AI, or public sector innovation.
• Proven experience managing complex, multi-stakeholder programs from research through to pilot or deployment.
• Advanced understanding of Agile principles, with a track record of applying them in multidisciplinary settings.
• Strong ability to navigate technical and non-technical audiences; excellent facilitation, communication, and decision-making skills.
• Familiarity with healthcare delivery systems, clinical workflows, or health IT infrastructure.
• Experience in data standardisation, tokenisation or clinical terminology mapping will be a plus

Preferred Qualifications

• Degree in computer science, engineering, public health, or related field; postgraduate qualifications a plus.
• Agile certifications (e.g., CSPO, SAFe PO/PM, or equivalent).
• Experience with public healthcare transformation, AI ethics, or large-scale digital health rollouts.
• Understanding of regulatory frameworks for health AI and data governance (e.g., SaMD, IMDRF, PDPA).

What you need to know

Successful candidate will be offered a 3-year contract, renewable. We regret that only shortlisted candidates will be contacted. For more information about CRIS and the Business Entities, visit our websites below:

CRIS – https://www.cris.sg

SCRI – https://www.scri.edu.sg

NHIC – https://www.nhic.sg

ACTRIS – https://www.actris.sg

PRECISE – https://www.npm.sg

STCC – https://www.stcc.sg

CADENCE – https://www.cris.sg/our-programmes/cadence/

SIMFONI - https://www.cris.sg/singapore-medical-foundation-ai-model-simfoni