Senior AI Engineer

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: .

Position Summary:

As a Senior AI Engineer on the AI Venture Studio team, you will be a hands-on senior individual contributor who leans into artificial intelligence (AI) to design and build impactful solutions to transform patients’ lives. This role is accountable for the AI-first engineering of cloud-native applications, agentic AI products, and the knowledge and context infrastructure that powers them. You will have access to the latest AI-centric tools and technologies to support activities such as the design of APIs and MCPs, cloud services orchestration, agent runtime deployment, workflow pipeline implementation, and reusable platform pattern development that enables AI Accelerator projects to move fast without giving up reliability, observability, security, or enterprise architectural alignment.

This role lives inside the AI Accelerator delivery model: six fully agile two-week sprints across a twelve-week cycle to build, test, validate, and prepare minimum viable products (MVPs) for broader organizational adoption and scaling. AI Accelerator projects focus on the most challenging and highest-upside pharma-specific problems across R&D, Commercialization, Manufacturing, and Enabling Functions where critical context is buried in unstructured knowledge files, multimodal documents and reports, operational records, and scientific evidence packages.

What Matters Most in This Role:

• Ship in cycles by demonstrating engineering progress and lessons learned every two weeks.

• Focus on AI-first solutioning that prioritizes BMS technology investments (AWS, Claude, LangSmith, etc.) with the best chance of meeting use case and project success metrics.

• Collaborate effectively with other engineers (AI, data, UI/UX, machine learning) and broader agile AI accelerator product teams.

• Demonstrate a curious and inquisitive mindset with broad technical adaptability while staying hands-on with frontier AI technologies, AI coding agents, and the latest agentic engineering capabilities.

Additional Key Responsibilities:

Cloud-Native Application and AI Engineering:

• Design, build, and deliver backend services and application components using Python/FastAPI, TypeScript/Node, or similar technologies that integrate LLM APIs, AI agents, retrieval systems, workflow engines, and enterprise systems to create scalable AI-powered solutions.

• Develop MCP-accessible services, tools, and skills that enable governed read, write, and search access to structured knowledge assets (e.g., Markdown, YAML), with versioning, auditability, and integration into cloud-native storage and identity patterns.

• Implement secure application patterns for authentication and authorization, including enterprise SSO, service-account and machine credential management, secrets management, input/schema validation, and secure service-to-service communication.

• Partner with frontend engineers throughout the software delivery lifecycle to define clean API contracts, streaming response patterns, error handling, and service-level behaviors that enable intuitive AI-powered user experiences.

Agent Engineering, Orchestration, and Knowledge Systems:

• Build and operate agentic applications using LangGraph, Claude Agent SDK, and related frameworks, including workflow state management, orchestration, tool use, loops, multi-agent collaboration, and durable execution patterns.

• Develop MCP servers, tools, and skills that expose governed enterprise capabilities to agents through secure, reusable, and observable interfaces.

• Design retrieval, memory, and context architectures using AWS-native services and data stores, including vector, graph, relational, cache, and object storage patterns that enable grounded and context-aware AI applications.

• Build evaluation, testing, and observability frameworks that measure agent quality, reliability, latency, cost, and business outcomes while enabling rapid iteration.

• Create reusable platform accelerators, deployment patterns, and golden paths for containerized, serverless, and production AI applications running on AWS.

Platform Engineering, DevOps, and Reliability:

• Build and maintain CI/CD pipelines, infrastructure-as-code, automated testing, evaluation frameworks, and release processes for cloud-native AI applications.

• Measure and improve reliability, quality, latency, cost, and business outcomes through observability, evaluation, and continuous delivery practices.

• Embed security, quality, and reliability controls into delivery pipelines, including automated testing, vulnerability scanning, regression suites, guardrails, and structured-output validation.

• Create isolated development and execution environments that support safe experimentation, reproducibility, auditability, and governed promotion of code and data assets.

• Develop and maintain reusable platform patterns, tooling, and engineering standards that accelerate the delivery of secure and scalable AI applications.

Technical Leadership, Collaboration, and Delivery:

• Translate business problems into technical architectures and delivery plans that align AI capabilities with measurable product outcomes.

• Drive MVPs toward production readiness by validating technical feasibility, reliability, scalability, security, and measurable business value.

• Rapidly prototype, validate, and iterate on emerging AI capabilities to identify scalable patterns and reduce technical uncertainty before broader adoption.

• Provide technical leadership through architecture reviews, code reviews, design mentorship, engineering standards, documentation, and reusable reference implementations.

• Communicate technical and cloud architecture trade-offs clearly, balancing speed, cost, reliability, security, compliance, scalability, and long-term maintainability.

Qualifications & Experience:

Required Qualifications:

• Bachelor’s or higher degree in Computer Science, Engineering, Science, or a related field.

• 5+ years of experience designing, building, and scaling software applications, cloud platforms, APIs, or distributed systems with increasing technical responsibility.

• Strong proficiency in Python and FastAPI and/or TypeScript/Node, or comparable backend application frameworks.

• Hands-on experience building and operating cloud-native applications on AWS.

• Experience designing and delivering AI-powered applications that integrate LLMs, retrieval systems, workflows, agents, or other AI capabilities into real-world user experiences.

• Experience building agentic AI applications using frameworks such as LangGraph, LangChain, PydanticAI, Claude Agent SDK, or similar technologies.

• Experience with containers, CI/CD, GitHub-based workflows, automated testing, environment configuration, and infrastructure-as-code such as Terraform, AWS CDK, or CloudFormation.

• Practical experience integrating enterprise LLM services such as Anthropic (preferred), OpenAI, Gemini, Grok, AWS Bedrock, or similar enterprise-approved AI services into AI-powered applications.

• Demonstrated understanding of the architectural patterns, trade-offs, and engineering practices required to scale AI applications from prototype to production, including reliability, observability, security, performance, and cost management.

• Working knowledge of secure and responsible AI application patterns including authentication, authorization, enterprise SSO, secrets management, auditability, model evaluation, guardrails, and secure application architecture.

• Demonstrated ability to effectively use AI coding agents and AI-assisted development tools such as Claude Code, Codex, Gemini CLI, Cursor, Windsurf, or GitHub Copilot to accelerate software delivery.

• Strong communication skills and comfort operating within fast-moving, cross-functional agile teams where ambiguity, rapid experimentation, and continuous learning are expected.

Desired Qualifications:

• Experience building MCP servers, MCP tools, FastMCP applications, or governed agent tooling ecosystems.

• Experience designing retrieval, memory, context, and knowledge architectures using vector stores, relational databases, graph databases, and enterprise knowledge systems.

• Experience developing multi-agent systems, workflow orchestration patterns, tool-calling architectures, durable execution, and long-running agent workflows.

• Experience with evaluation-driven development, agent testing, benchmark creation, AI observability, and platforms such as LangSmith, promptfoo, or similar tooling.

• Experience designing semantic layers, natural-language-to-SQL systems, analytics agents, or governed data access patterns.

• Experience building sandboxed execution environments, provenance tracking, version-controlled data workflows, and audit-friendly agent architectures.

• Experience deploying, operating, and supporting production AI applications with real-world users, service-level objectives, monitoring, incident response, and operational support processes.

• Experience partnering closely with frontend engineers on chat, copilot, citation/provenance, streaming, and human-in-the-loop user experiences.

• Active GitHub contributions, open-source participation, personal projects, or other demonstrated examples of building with modern AI technologies.

• Experience within life sciences, pharmaceutical, healthcare, scientific, or other regulated industries.

#AICP

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Cambridge Crossing: $151,280 - $183,319 
Madison - Giralda - NJ - US: $137,530 - $166,654
Princeton - NJ - US: $137,530 - $166,654 
Seattle - WA: $151,280 - $183,319


The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

​Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at .

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at [email protected]. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1602673 : Senior AI Engineer