Principal Agentic Workflow & AI Engineer, Biologics Discovery

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at .

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Data Analytics & Computational Sciences

Job Sub Function:

Data Engineering

Job Category:

Scientific/Technology

All Job Posting Locations:

Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

About the opportunity

Johnson & Johnson Innovative Medicine is seeking a Principal Agentic Workflow & AI Engineer to help build the agentic layer of our Biologics Discovery data engine. This is an opportunity to be one of the early, senior experts shaping how agentic AI workflows automate secondary data processing, orchestrate analyses, and connect experimental outputs to models and decisions across the DMTL (design-make-test-learn) cycle. You will work at the intersection of scientific experimentation, data pipelines, AI systems, and lab automation.

This position will be located at one of our office locations in either Spring House, PA (preferred), Titusville, NJ, or Raritan, NJ. (No remote option.)

Why this role matters: Getting biologics data to flow reliably through our systems is a critical, often underestimated challenge, and there is significant opportunity to automate secondary analysis. This role brings agentic AI and intelligent automation to compress cycle time, reduce manual intervention, and improve reproducibility - transforming today’s hands-on processes into scalable, connected, intelligent discovery workflows. It is a strategically visible Principal-level role, central to our next-generation discovery automation.

Why This Role Is Unique

This is a rare chance to architect how scientific and physical AI come together to steer design and execution in the lab - not just automating steps but building a next-generation discovery engine in a large pharma setting. As a Principal individual contributor, your work will be among the most visible and influential on the team and will directly accelerate how tomorrow's therapies are discovered.

Position Summary

As a Principal Agentic Workflow & AI Engineer, you will design and build agentic workflows and orchestration that own the scientific data analysis and secondary processing logic our team delivers. You will translate scientific priorities into automation and AI roadmaps, and build real-time pipelines connecting automation software, data stores, models, and compute.

You will partner across Discovery, Data Science, In Silico Discovery (ISD), our Enterprise Generative AI team, and our data-infrastructure and lab-automation teams to enable closed-loop feedback so that each experimental cycle improves downstream models and decisions - timed to lab-automation readiness as new automation infrastructure comes online. You will also set technical direction and mentor other team members.

Key Responsibilities

Agentic Orchestration & Integration

• Design, configure, and continuously improve agentic workflows that automate secondary analysis for biologics discovery assays, replacing fragile manual and ad-hoc scripted steps.
• Build or oversee real-time pipelines connecting automation software, data stores, models, and compute environments.
• Partner with IT and platform teams to implement resilient APIs, observability, versioning, and workflow orchestration end-to-end.
• Partner with our Enterprise Generative AI team to build on shared GenAI platforms, models, and agentic frameworks - extending them for biologics discovery rather than duplicating enterprise capabilities.
• Partner with ontology and MLOps colleagues so automated workflows produce semantically consistent, reusable data and deploy reliably into production.

AI-Driven Scientific Learning

• Design workflows optimized for AI-driven learning, not just throughput, enabling closed-loop feedback across the design-make-test-learn (DMTL) cycle.
• Collaborate with discovery scientists, AI/ML scientists, and data engineers so experimental outputs improve downstream property models and decision-making.
• Ensure data generated through agentic workflows is high-quality, traceable, interoperable, and AI-ready, with strong metadata, provenance, and lineage.
• Identify opportunities to apply agentic AI to compress cycle time and improve reproducibility.

Technical Leadership

• Set technical direction and standards for agentic workflows and mentor engineers and data scientists across the AI/ML space.
• Evaluate and pilot emerging agentic AI methods, frameworks, and tools, guiding where the team invests.
• Represent the team's agentic work in cross-functional technical forums, aligning approaches with partner teams and enterprise standards.

Qualifications

Required

• Advanced degree (Ph.D. preferred) in Computer Science, Engineering, or a related computational field.
• At least 3 years experience building scientific workflow orchestration, automation software, including experience in agentic workflows and technical leadership responsibilities.
• Hands-on experience designing real-time or near-real-time data pipelines and integrating complex and heterogeneous scientific data and instrument outputs.
• Experience applying agentic AI and modern LLM-based agents (or comparable intelligent-automation systems) to scientific or laboratory workflows.
• Experience building on enterprise or shared GenAI platforms and retrieval-augmented approaches (e.g., RAG or GraphRAG) rather than standing up capabilities from scratch.
• Ability to translate scientific objectives into practical, scalable technical solutions and to set technical direction for others.
• Strong communication and stakeholder management with comfort operating in ambiguity and representing work to leadership in matrixed organizations.

Preferred

• Experience in drug discovery domains such as biologics, high-throughput experimentation, or imaging.
• Exposure to lab automation, robotic systems, or cyber-physical systems for R&D.
• Familiarity with MLOps/DevOps, workflow engines, and production-grade monitoring/observability.
• Understanding of FAIR data, ontologies, semantic models, lineage/provenance, and AI-ready data standards.

This position will be located at one of our office locations in either Spring House, PA (preferred), Titusville, NJ, or Raritan, NJ. (No remote option.)

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

If you are under 18 years of age, you (the candidate) may need to obtain the necessary working papers or other documentation required by state law to start the assignment, as well as get a parent’s consent for the background check.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via , internal employees contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position is $117,000 to $201,250. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

Employees are eligible for the following time off benefits:
Vacation – up to 120 hours per calendar year
Sick time - up to 40 hours per calendar year
Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year
Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

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Required Skills:

Preferred Skills: