Lead Software Engineer at Twin Health – Remote | Jobyssey

Twin Health

At Twin Health, we empower people to improve and prevent chronic metabolic diseases, like type 2 diabetes and obesity, with a new standard of care. Twin Health is the only company applying AI Digital Twin technology exclusively toward metabolic health.

We start by building a dynamic model of each person’s metabolism — drawing on thousands of data points from CGMs, smartwatches, and meal logs — that maps their personal path to better health. Guided by a dedicated clinical care team, our members have lowered their A1C below the diabetes range, achieved lasting weight loss, and reduced or even eliminated medications, all while living healthier, happier lives.

Working here

Our team at Twin Health is passionate, talented, and united by a shared purpose: to improve the metabolic health and happiness of our members. We believe in empowering every Twin to make a meaningful impact for our members, our clients, and each other, while enjoying a supportive, collaborative work environment.

Twin has been recognized not only for our innovation but also for our culture, including: Innovator of the Year by the Employer Health Innovation Roundtable (EHIR), selected to CB Insights’ Digital Health 150, and named one of Newsweek’s Top Most Loved Workplace® .

With more than $100 million raised in recent funding, including a $53 million Series E round in 2025 led by Maj Invest, and a $50 million investment in 2023 led by Temasek, Twin is scaling rapidly across the U.S. and globally. Backed by leading venture firms like ICONIQ Growth, Sequoia, Sofina, Temasek, and Peak XV, we are building the most impactful digital health company in the world.

Join us as we reinvent the standard of care in metabolic health.

Opportunity

We are seeking a Lead Software Engineer to join our Copilot team and play a key role in shaping the technical direction and execution of our new AI-powered platform. This platform is designed to optimize and enhance the efficiency of our clinical operations teams.

This role offers a compelling opportunity at the intersection of backend engineering, healthcare technology, and system integrations. As a technical leader, you will drive architectural decisions, lead complex initiatives, and influence engineering best practices. You will work closely with AI, mobile, and other engineering teams, as well as clinical operations stakeholders, to streamline workflows and ultimately improve the member experience.

Responsibilities

Lead the end-to-end delivery of Copilot product capabilities for the care teams, from product discovery and technical design through implementation, launch, measurement, and production operations.
Partner with Product Managers and clinical or business stakeholders to define priorities, evaluate tradeoffs, and translate customer and business needs into an executable product roadmap.
Establish, own, and drive measurable product and business outcomes; ensure appropriate instrumentation and use post-launch results to guide iteration.
Break complex initiatives into clear workstreams, delegate ownership effectively across engineers, manage dependencies, and hold the team accountable for high-quality delivery.
Lead full-stack technical direction across user experiences, backend services, data flows, and system integrations while remaining hands-on in Python and FastAPI backend development.
Design, develop, and scale reliable microservices and APIs using Python/FastAPI; contribute to or integrate with Java/Spring Boot services where appropriate.
Make and document architectural decisions for complex, event-driven, distributed systems, including reliability, scalability, security, and operational tradeoffs.
Collaborate closely with AI/ML, Data Platform, Infrastructure, mobile, and other engineering teams to deliver cohesive product capabilities and resolve cross-team dependencies.
Develop and productionize AI-powered capabilities, including evaluation, guardrails, observability, and continuous-improvement workflows.
Mentor engineers, provide technical direction and review, and improve the engineering practices needed for safe, frequent releases and reliable production operation.
Take on additional responsibilities as needed.

Qualifications

6+ years of professional software engineering experience, including recent hands-on backend or full-stack product development.
Demonstrated experience leading a significant project or team through end-to-end delivery, including planning work, delegating ownership, coordinating dependencies, and making technical and delivery decisions.
Demonstrated experience partnering with Product Managers and business stakeholders to shape priorities, make tradeoffs, and own measurable customer or business outcomes.
Experience personally owning and delivering customer-facing products from discovery or definition through launch, measurement, iteration, and production support.
Full-stack technical leadership experience, with strong hands-on Python backend expertise and experience building microservices using FastAPI.
Experience personally designing complex, event-driven systems and distributed architectures, including making documented scalability, reliability, and operational tradeoffs.
Strong knowledge of API design, authentication and authorization, data modeling, production debugging, and performance optimization.
Ability to communicate technical decisions, risks, tradeoffs, and progress clearly to engineering, product, clinical, and business audiences.

Preferred Qualifications

Experience developing and operating AI agents or AI-powered products in production, including evaluation, safety controls, monitoring, and iterative improvement.
Experience building products in healthcare, regulated environments, or fast-paced growth-stage companies.

Compensation and Benefits

The compensation range for this position is $220,000 - $240,000 annually.

Twin has an ambitious vision to empower people to live healthier and happier lives, and to achieve this purpose, we need the very best people to enhance our cutting-edge technology and medical science, deliver the best possible care, and turn our passion into value for our members, partners and investors. We are committed to delivering an outstanding culture and experience for every Twin employee through a company based on the values of passion, talent, and trust. We offer comprehensive benefits and perks in line with these principles, as well as a high level of flexibility for every Twin

A competitive compensation package in line with leading technology companies
A remote and accomplished global team
Opportunity for equity participation
Unlimited vacation with manager approval
16 weeks of 100% paid parental leave for delivering parents; 8 weeks of 100% paid parental leave for non-delivering parents
100% Employer sponsored healthcare, dental, and vision for you, and 80% coverage for your family; Health Savings Account and Flexible Spending Account options
401k retirement savings plan

Salary range for US jobs

US Salary Range

$220,000—$240,000 USD

We have been made aware of fraudulent interview requests being sent using the Twin Health's name. All communications will come from official Twin Health channels and a email address. We will never ask you to complete a text interview or request financial details during the interview process.

Lead Software Engineer

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